Morphological Changes of Gingiva in Streptozotocin Diabetic Rats

نویسندگان

  • C. Tesseromatis
  • A. Kotsiou
  • H. Parara
  • E. Vairaktaris
  • M. Tsamouri
چکیده

Gingivitis and periodontitis are chronic bacterial diseases of the underlying and surrounding tooth tissues. Diabetes mellitus is responsible for tooth deprivation both by decay and periodontal disease. The streptozotocin-induced diabetes results in a diabetic status in experimental animals similar to that observed in diabetes patients. The aim of the study was to investigate the relationship between the gingival lesions and the microangiopathy changes in streptozotocin-induced diabetes mellitus. Forty male Wistar rats were divided into two groups (control and experimental). Diabetes mellitus was induced by 45 mg/kg IV streptozotocin. The histological investigation of the marginal gingival and the relevant gingival papilla showed inflammation of the lamina propria and the squamous epithelium as well as marked thickness of the arteriole in the diabetic group, but no changes were observed in the control group. The results suggested a probable application of a routine gingival histological investigation in diabetic patients in order to control the progress of disease complications. It may be concluded that histological gingival investigation can be used as a routine assay for the control of the diabetic disease and prevention of its complications.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Morphological Changes in Hippocampal Ca1 Area in Diabetic Rats: A Golgi-impregnation Study

Background and Objective: Although diabetes mellitus is known to be one of the risk factors for dementia but neuropathic changes in the brain of diabetic patients have not been completely revealed. Therefore, this research study was done to evaluate structural changes in pyramidal neurons of hippocampal ...

متن کامل

The Effects of Basil on Changes in Blood Glucose and Testosterone Levels in Streptozotocin-Induced Diabetic Rats

Abstract          Background and Objective: According to Iranian, Asian, Indian, and Chinese traditional medicine, basil is used in the treatment of different diseases. In this study, the effect of basil on lowering the blood glucose was examined in healthy and diabetic rats.         Methods: Sixty Wistar...

متن کامل

The Histological, Histomorphometrical and Histochemical Changes of Testicular Tissue in the Metformin Treated and Untreated Streptozotocin-Induced Adult Diabetic Rats

In this investigation, diabetes was induced in adult male Sprague-Dawley rats by single intraperitoneal injection of streptozotocin (STZ) at 45 mg kg-1 of body weight. A group comprised of 8 diabetic rats was treated with metformin at 100 mg kg-1 of body weight for reducing the elevated blood glucose level. The results revealed that, in the untreated diabetic rats, the body and testicular weigh...

متن کامل

Soybean feeding improves vascular dysfunction and atte-nuates oxidative stress in streptozotocin-diabetic rats

Background and Objective: In this research, the effect of chronic dietary soybean aqueous extract on aortic reactivity of streptozotocin (STZ)-diabetic rats was investigated. Materials and Methods: STZ-diabetic rats were treated with soybean aqueous extract for two months after diabetes induction. Contractile reactivity to KCl and phenylephrine (PE) and relaxation response to acetylcholine (ACh...

متن کامل

Effects of Colocynth (Citrullus colocynthis) Pulp on Serum Levels of Testosterone and Changes in Reproductive Organs in Streptozotocin-Induced Diabetic Rats

Introduction: Investigating the effects of colocynth pulp on levels of testosterone and changes in the reproductive system organs in streptozotocin-induced diabetic rats. Methods: In this study, 32 Wistar rats were divided into four groups of normal (N), normal+colocynth pulp (N+C), diabetic control (D), and diabetic+colocynth pulp (D+C). Groups N and D received orally 2 mL normal saline for tw...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2009  شماره 

صفحات  -

تاریخ انتشار 2009